Naltrexone
Blocks opioid receptors involved in alcohol's 'buzz', reducing reward and heavy-drinking days. Taken daily or as needed before drinking (the Sinclair Method).
Medications
A personalized plan, built from proven options
Your addiction specialist reviews your health history, goals and preferences — without judgment, and with no pressure to quit completely — to recommend the right medication or combination.
GLP-1 agonists (semaglutide)
Originally for diabetes and weight, GLP-1 drugs act on brain reward pathways. Early clinical trials and large observational studies show reduced cravings and drinks per day. May suit members who also want metabolic or weight benefits.
Acamprosate
Helps restore brain chemistry balance after stopping, easing lingering discomfort and supporting abstinence.
Disulfiram
Causes unpleasant reactions if alcohol is consumed; used selectively for highly motivated members.
GLP-1 receptor agonists are not FDA-approved for alcohol use disorder. Availability depends on medical eligibility, state regulations and pharmacy supply. PathReset is self-pay only; we do not bill insurance.
